Bioactive Nutraceuticals and Dietary Supplements in Neurological and Brain DiseasePrevention and Therapy
2015, Pages 113–124
Chapter 12 – Ginkgo biloba Extracts in Neurological Disorders Therapy: Clinical Trials
Abstract
Aging is the major risk factor for neurodegenerative diseases such as Alzheimer’s and Parkinson’s diseases. The standard Gingko biloba
leaf extract EGb 761 has been given routinely as a prescription drug in
many countries for Alzheimer’s dementia. Numerous clinical data have
demonstrated possible improvement of dementia by EGb 761 in
neurodegenerative patients. Polypotent and multitarget actions of EGb
761 may underlie its clinical efficacy. EGb 761 exhibits a good
side-effect profile in clinical studies. Therefore, we discuss EGb 761
in neurological disorders therapy in this chapter.
Keywords
- Ginkgo biloba;
- diterpenoids;
- flavonoids;
- Alzheimer’s disease;
- neurodegenerative diseases;
- dementia;
- EGb 761;
- clinical trials
