Volume 40, Issue 2, 2015, Pages 87-99
a
Faculty of Medicine, Toho University, Ota-ku, Tokyo, Japan
b Ning University of Chinese Medicine, Nanjing, China
b Ning University of Chinese Medicine, Nanjing, China
Abstract
Regarding the effects of electro-acupuncture
for severe hypertension, we assessed its acute cardiovascular
consequences with 4 subjects of the chronic atrioventricular block dogs
having severe hypertension and chronic heart failure. The electro-acupuncture
consisting of 2 mA at 2 Hz frequency was carried out for 30 mm at
Renying (ST-9) and Taichong (LR-3) every other day. Seven sessions were
performed within 2 weeks. In the 1st and 7th sessions, the animals were
anesthetized with pentobarbital to analyze the effects of the electro-acupuncture
on cardiovascular variables. No significant change was detected in any
of the basal control values of the cardiohemodynamic or
electrophysiological variables between the 1st and 7th sessions. During
the 1st session, electo-acupuncture
produced a peak increase in mean blood pressure by 8.7% at 35 mm
(p<0.05), whereas during the 7th session the peak increase was 6.5%
at 35 mm (p=0.06). There was no significant change in the cardiac
output, total peripheral resistance, a product of the heart rate and
systolic blood pressure (=double product) reflecting myocardial oxygen
consumption, QRS width or QT interval during the electrical stimulation
in the 1St or 7th session. The results suggest that electroacupuncture
may not exert lethal adverse effect except the vasopressor response, but
that it can decrease the treatment-induced sympathetic response
including vasopressor reaction and tachycardia. Since electro-acupuncture
may have some potential to induce hypertensive crisis at the beginning,
clinicians have to pay attention on its use for patients with
hypertension. Copyright © 2015 Cognizant Communication Corp. Printed in
the USA.
Author keywords
Atrio-ventricular block; Blood pressure; Electro-acupuncture; Electrocardiogram; Heart rate; Safety assessment; Severe hypertension
Indexed keywords
EMTREE medical terms: acupuncture;
adverse effects; animal; atrioventricular block; blood pressure;
chronic disease; complication; disease model; dog; electroacupuncture;
female; heart failure; heart output; human; hypertension; male;
pathophysiology; vascular resistance
MeSH: Acupuncture
Points; Animals; Atrioventricular Block; Blood Pressure; Cardiac
Output; Chronic Disease; Disease Models, Animal; Dogs;
Electroacupuncture; Female; Heart Failure; Humans; Hypertension; Male;
Vascular Resistance
Medline is the source for the MeSH terms of this document.
Medline is the source for the MeSH terms of this document.
ISSN: 03601293
CODEN: AEREDSource Type: Journal
Original language: English
PubMed ID: 26369252Document Type: Article
Publisher: Cognizant Communication Corporation
