Evid Based Complement Alternat Med. 2015;2015:840742. doi: 10.1155/2015/840742. Epub 2015 Oct 4.
Abstract
Despite widespread popular use of complementary and alternative medicine (CAM) therapies, a rigorous evidence based on the efficacy of compound kushen injection (CKI) for cancer-related pain
is lacking. In this study, we evaluated the efficacy and safety of
compound kushen injection and provided information for current or future
research and clinical application. Sixteen trials were identified with a
total of 1564 patients. The total pain relief rate of CKI plus chemotherapy is better than chemotherapy except for colorectal cancer.
The treatment groups achieved a reduction in the incidences of
leukopenia and gastrointestinal, hepatic, and renal functional lesion.
However, there is paucity of multi-institutional RCTs evaluating
compound kushen injection for cancer pain
with adequate power, duration, and sham control. The quantity and
quality of RCTs are lower so that we still have to boost the research
level through scientific design and normative report.
- PMID:
- 26504481
- [PubMed]
- PMCID:
- PMC4609400
