Front Pharmacol. 2015 Nov 3;6:259.
Abstract
Syzygium cumini (Myrtaceae) is a worldwide medicinal plant traditionally used in herbal
medicines due to its vaunted properties against cardiometabolic
disorders, which include: antihyperglycemic, hypolipemiant,
antiinflammatory, cardioprotective, and antioxidant activities. These
properties have been attributed to the presence of bioactive compounds
such as phenols, flavonoids, and tannins in different parts of the
plant, albeit the knowledge on their mechanisms of action is scarce.
This mini-review highlights the cardiometabolic properties of S. cumini
by correlating its already identified phytochemicals with their
described mechanisms of action. Data herein compiled show that some
compounds target multiple metabolic pathways; thereby, becoming
potential pharmacological tools. Moreover, the lack of clinical trials
on S. cumini usage makes it a fruitful field of interest for both scientific community and pharmaceutical industry.
KEYWORDS:
black plum; complementary and alternative medicine; ethnopharmacology; jamun; medicinal plants; metabolic syndrome; myrtaceae; phenolic compounds- PMID:
- 26578965
- [PubMed - as supplied by publisher]
- PMCID:
- PMC4630574
