- International Research and Production Holding “Phytochemistry”, Karaganda, 100009, Republic of Kazakhstan
- Received 4 June 2015, Revised 18 November 2015, Accepted 22 November 2015, Available online 25 November 2015
Abstract
This
review summarizes the results of own research on chemical modification
of the molecule of sesquiterpene lactone arglabin from Artemisia glabella
Kar. et Kir. Over 70 new arglabin derivatives were obtained which are
polyfunctional compounds with oxy functions, atoms of haloids,
phosphorus, nitrogen, cyclopropane fragments. For the first time the
results of bioscreening of new arglabin derivatives are reported.
Graphical abstract
Keywords
- Artemisia glabella Kar. et kir.;
- Sesquiterpene lactone arglabin;
- Structure-activity;
- Antitumoral;
- Antifungal;
- Phagocytosis stimulating;
- Anti-inflammatory;
- Antimicrobial activities and immunomodulatory action
Copyright © 2015 Published by Elsevier B.V.
