Abstract
ABSTRACT
Qualitative composition and content of phenolic compounds in dry extract obtained from plum leaves have been studied. Seven phenolic substances were found, including three hydroxycinnamic acids and four flavonoids. The dominant substances were chlorogenic acid (2436.89 mg/100g) and rutin (926.32 mg/100g). Free monosugars as glucose and rhamnose were identified in the extract and their amount determined by HPLC. Obtained results showed prospects of creating on the base of plum leaves dry extract a new drug with antioxidant activity.
Qualitative composition and content of phenolic compounds in dry extract obtained from plum leaves have been studied. Seven phenolic substances were found, including three hydroxycinnamic acids and four flavonoids. The dominant substances were chlorogenic acid (2436.89 mg/100g) and rutin (926.32 mg/100g). Free monosugars as glucose and rhamnose were identified in the extract and their amount determined by HPLC. Obtained results showed prospects of creating on the base of plum leaves dry extract a new drug with antioxidant activity.
Keywords
plum; leaves; extract; phenolic compounds
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Qaiser J, Naveed A.The pharmacological activities of prunes: The dried Plums. Journal of Medicinal Plants Research. 2011; 5(9): 1508-1511.
Pharmaceutical encyclopedia. 2nded.: Chairman Ed. Council Chernykh V.P. Кiev: «МОRІОN»; 2010. 1290 p. Ukrainian.
Vovk G, Koshovyi O, Komissarenko A. Study of dry extract phenolic compounds of sage leaves, obtained by complex processing after tincture production. Collection of scientific works of staff members of NMAPE. 2014; 4:237 - 40.
Chen L., Hrazdina G. Structural aspects of anthocyanin-flavonoid complex formation in plant color. Phytochemistry. 1981;20:297-3.
Court W. H. P. L. C. reverse phase of naturally occurring phenolic compounds. J. Chromatogr. 1977;130:287-91.
Mabry T, Markham K, Thomas M. The Systematic Identification of Flavonoids. New York: Springer-Verlag; 1970.
Mс. Murrough I, Hennigan G, Loughrey M. Quantitative analysis of hop flavonols using H.P.L.C. J. Agric. Food Chem. 1982;30:1102-6.
Kovaleva A, Abdulkafarova E. Phenolic compounds from Potentilla anserine. Chemistry of Natural Compounds. 2011;47(3):446-7.
Bouayed J, Rammal H, Dicko A, Younos C, Soulimani R. Chlorogenic acid, a polyphenol from Prunus domestica (Mirabelle), with coupled anxiolytic and antioxidant effects. J Neurol Sci. 2007;262(1-2):77-84.
Al-Dhabi1 N, Arasu1 M, Park C. Ha, Park S. Un. An up-to-date review of rutin and its biological and pharmacological activities. EXCLI Journal. 2015;14:59-63.
DOI: http://dx.doi.org/10.14748/ssp.v2i2.1302
