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CSIR Unit for Research and Development of Information Products “Tapovan”, S.No.113, 114, NCL Estate, Pashan Road, Pune, Maharashtra, India

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Abstract

Toxic plants are found to have potential therapeutic activities. They have been used in the treatment of a number of dis-eases. Recently there is an increasing demand and interest in bioactive natural products from plants for the purpose of their use in herbal medicine. So critical evaluation of their toxicity has become necessary. This article provides the de-tailed toxicity information of the phytochemical constituents from the toxic plant Anagallis arvensis (Family Primula-ceae). The plant is toxic to ruminants but it has great potential to treat diseases like Gout, Leprosy, Epilepsy, Urinary infection etc. The phytochemical constituents isolated from the toxic plant have Antibacterial, Antifungal, Antiviral, An-titumour, Antidiabetic, Antidepressant, Anti-inflammatory and Hepatoprotective activities. Some bioactives are having therapeutic activity, no reported toxicity and were predicted to be less toxic. Many actives from this plant have not been explored for any activity and their toxicity has not been determined. These actives were found to be less toxic through the toxicity prediction tool. This study would be important for exploiting the potential of such actives which may further prove to be promising natural products for medicinal and cosmetic use. © 2016, International Journal of Toxicological and Pharmacological Research. All rights reserved.

Author keywords

Anagallis; Bioactive; Prediction; Primulaceae; Toxicity; Traditional medicine

ISSN: 09755160Source Type: Journal Original language: English

Document Type: Article

Publisher: International Journal of Toxicological and Pharmacological Research

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Friday 1 July 2016

Evaluation of potential toxicity of bioactives of anagallis arvensis- A toxic plant

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References (57)

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