Changes in Approaches to the Normalization of Heavy Metal Contents in Medicinal Herbs and Herbal Medicines (Review)

Pharmaceutical Chemistry Journal

Volume 49, Issue 7, 1 October 2015, Pages 490-494

Kuz’mina, N.E., 

Shchukin, V.M., 

Severinova, E.Y., 

Yashkir, V.A., 

Merkulov, V.A.

 

Scientific Center for Expert Assessment of Substances for Medicinal Use, Russian Ministry of Health, Building 8, Petrovskii Boulevard, Moscow, Russian Federation 

View references (51)

Abstract

Analysis of normative documents identified a tendency to eliminate differences in approaches to the normalization of heavy metals contents in medicinal substances, medicinal herbs, and herbal medicines. The current main principle of the normalization of heavy metals is the principle of selective assay. © 2015, Springer Science+Business Media New York.

Author keywords

acceptable limits; heavy metals; herbal medicines; medicinal herbs; normalization

ISSN: 0091150X CODEN: PCJOASource Type: Journal Original language: English

DOI: 10.1007/s11094-015-1312-yDocument Type: Review

Publisher: Springer New York LLC

References (51)

View in search results format

• Page
 
• • Export |
  • Print |
  • E-mail |
  • Create bibliography

• 
  1

  Calixto, J.B.

  Efficacy, safety, quality control, marketing and regulatory guidelines for herbal medicines (phytotherapeutic agents)
  (2000) Brazilian Journal of Medical and Biological Research, 33 (2), pp. 179-189. Cited 340 times.
  

  • View at Publisher
• 
  2

  (2013) S. Y. Pan, S. F. Zhou, S. H. Gao, et al., “New perspectives on how to discover drugs from herbal medicines: CAM’s outstanding contribution to modern therapeutics,” Evidence-Based Complementary and Alternative Medicine (2013)
  Article ID
  

  •  
• 
  3

  Lahlou, M.
  (2013) Pharmacol. Pharmacy, 4, pp. 17-31. Cited 30 times.
  

  •  
• 
  4

  Furini, A.
  (2012) Plants and Heavy Metals, pp. 2-3.
  (ed), Springer, New York
  

  •  
• 
  5

  Standard, R.S.
  (2003) GOST R 17.4.3.07 – 2001, Conservation of Nature. Soils. Requirements for the Properties of Sewage Sludge for Use as Fertilizers [in Russian]
  Gosstandart Rossii, Moscow
  

  •  
• 
  6

  Il’in, V.B.
  (1991) Heavy Metals in Soil-Plant Systems [in Russian]. Cited 3 times.
  Nauka, Novosibirsk
  

  •  
• 
  7

  Hodgson, E.
  (2010) A Textbook of Modern Toxicology, pp. 49-55.
  (ed), JohnWiley & Sons, Inc., Hoboken, NJ
  

  •  
• 
  8

  Herbal Drugs, monograph 1433, European Pharmacopoeia (2011), 8th edition
  http://www.edgm.eu
  

  •  
• 
  9

  Herbal Drug Preparation, monograph 1434, European Pharmacopoeia (2011) 8th edition
  http://www.edgm.eu
  

  •  
• 
  10

  USSR Pharmacopeia [in Russian], Medgiz, Moscow (1952), edition VIII
  

  •  
• 
  11

  State Pharmacopeia of the Russian Federation [in Russian], Scientific Center for Expert Assessment of Substances for Medical Use, Moscow (2007), XII edition, Part I, pp. 119 – 123
  

  •  
• 
  12

  USSR State Pharmacopeia [in Russian], Meditsina, Moscow (1968), edition X, pp. 748 – 755
  

  •  
• 
  13

  USSR State Pharmacopeia [in Russian], Meditsina, Moscow (1987), edition XI, Part 1, pp. 165 – 175
  

  •  
• 
  14

  Japanese Pharmacopoeia XVI, The National Institute of Health Sciences (2011), pp. 29 – 30, 37 – 39;
  http://www.pmda.go.jp/english/pharmacopoeia/online.html
  

  •  
• 
  15

  Heavy Metals, General chapter •, USP 37/NF 32 (2014);
  http://www.uspnf.com/
  

  •  
• 
  16

  Heavy Metals, General chapter 2.4.8, European Pharmacopoeia, 8th ed. (2011);
  http://www.edgm.eu
  

  •  
• 
  17

  Limit Tests, British Pharmacopoeia, Vol. V, Appendix VII (2013);
  http://www.mhra.gov.uk/pharmacopoeia
  

  •  
• 
  18

  Pharmacopoeia of the People’s Republic of China, Vol. 2, Appendix VIII. Chinese Pharmacopoeia Commission, People Medical Publishing House (2005), pp. A-62-A-65
  

  •  
• 
  19

  Bowen, J.E.
  (1969) Plant Physiol., 44, pp. 255-261. Cited 81 times.
  COI: 1:CAS:528:DyaF1MXosV2qtQ%3D%3D, PID: 16657055
  

  •  
• 
  20

  Antonovics, J., Bradshaw, A.D., Turner, R.G.

  Heavy Metal Tolerance in Plants
  (1971) Advances in Ecological Research, 7 (C), pp. 1-85. Cited 560 times.
  doi: 10.1016/S0065-2504(08)60202-0
  

  • View at Publisher
• 
  21

  Abutalybov, M.T.
  (1961) Significance of Trace Elements in Agriculture [in Russian]
  Azerneshr, Baku
  

  •  
• 
  22

  Standard, S.
  (1980) GOST 24027.2–80, Raw Materials for Medicinal Plants. Methods for Assay of Moisture Content, Ash Content, Extractable Substances and Tannins, and Essential Oils [in Russian]
  Standards Press, Moscow
  

  •  
• 
  23

  USSR State Pharmacopeia SSSR [in Russian], Meditsina, Moscow (1990), XI edition, Vol. 2, pp. 148 – 149, 160 – 161, 252 – 256
  

  •  
• 
  24

  USSR State Pharmacopeia [in Russian], Meditsina, Moscow (1987), edition X, pp. 207 – 208, 278 – 279, 290 – 291, 295 – 297, 311 – 312, 342 – 343, 577 – 579, 614 – 615, 700
  

  •  
• 
  25

  Herbal Drugs, Herbal Drug Preparations and Herbal Medicinal Products, British Pharmacopoeia, V. IV (2013);
  http://www.mhra.gov.uk/pharmacopoeia
  

  •  
• 
  26

  Elemental Impurities – Limits, General chapter •, USP 37/NF32 (2014);
  http://www.uspnf.com/
  

  •  
• 
  27

  Fats and Fixed Oils, General chapters , USP 37/NF32 (2014);
  http://www.uspnf.com/
  

  •  
• 
  28

  Elemental Contaminants in Dietary Supplements, General chapter , USP 37/NF32 (2014);
  http://www.uspnf.com/
  

  •  
• 
  29

  Elemental Impurities – Procedures, General chapter •, USP 37/NF32 (2014);
  http://www.uspnf.com/
  

  •  
• 
  30

  Botanical Extracts, General Chapter , USP 37/NF32 (2014);
  http://www.uspnf.com/
  

  •  
• 
  31

  Articles of Botanical Origin, General Chapter , USP 37/NF32 (2014);
  http://www.uspnf.com/
  

  •  
• 
  32

  Monographs for Preparations Related to Crude Drugs, Japanese Pharmacopoeia the XVI ed., The National Institute of Health Sciences (2011), pp. 21 – 23;
  http://www.pmda.go.jp/english/pharmacopoeia/online.html
  

  •  
• 
  33

  Tests for Crude Drugs. General Chapter 5, Japanese Pharmacopoeia the XVI ed., The National Institute of Health Sciences (2011), pp. 117 – 120;
  http://www.pmda.go.jp/english/pharmacopoeia/online.html
  

  •  
• 
  34

  Pharmacopoeia of the People’s Republic of China, Vol. 2, Appendix VII, Chinese Pharmacopoeia Commission, People Medical Publishing House (2005), pp. A-56-A-58
  

  •  
• 
  35

  Pharmacopoeia of the People’s Republic of China, Vol. 1, Appendix IX. Chinese 54. Pharmacopoeia Commission, People Medical Publishing House (2005), pp. A-57-A-61
  

  •  
• 
  36

  Heavy Metals in Herbal Drugs and Fatty Oils, General Chapter 2.4.27., European Pharmacopoeia the 8th ed., Supplement 8.2. (2014);
  http://www.edgm.eu
  

  •  
• 
  37

  Zyrin, N.G., Kaplunova, E.V., Serdyukova, A.V.
  (1985) Khim. Sel’sk. Khoz., 23 (6), pp. 45-48.
  

  •  
• 
  38

  Chernykh, N.A.
  (1991) Agrokhimiya, 3, pp. 68-76. Cited 2 times.
  

  •  
• 
  39

  Foy, C.D., Chaney, R.L., White, M.C.
  (1978) Ann Rev. Pl. Phys., 29, pp. 511-526. Cited 1176 times.
  

  •  
• 
  40

  Freedman, B., Hutchinson, T.C., Lepp, N.W.
  (1981) Effect of Heavy Metal Pollution on Plants, pp. 35-94. Cited 35 times.
  (eds), 2, Applied Science Publishers, London and New Jersey
  

  •  
• 
  41

  Jiumura, K., Ito, H., Chino, M.
  (1977) Proc. Inst. Sem
  SEFMIA, Tokyo
  

  •  
• 
  42

  Reconsideration of Normative Documentation for Medicinal Substances and Medicinal Raw Plant Materials [in Russian]
  (1995) URL: http://russia.bestpravo.ru/fed1995/data03/tex15545.htm
  

  •  
• 
  43

  Blake, K.B.
  (1995) Pharm. Forum, 21 (6), pp. 1632-1637. Cited 11 times.
  

  •  
• 
  44

  Wang, T., Wu, J., Hartman, R., Jia, X., Egan, R.S.

  A multi-element ICP-MS survey method as an alternative to the heavy metals limit test for pharmaceutical materials
  (2000) Journal of Pharmaceutical and Biomedical Analysis, 23 (5), pp. 867-890. Cited 46 times.
  doi: 10.1016/S0731-7085(00)00361-7
  

  • View at Publisher
• 
  45

  WHO Guidelines for Assessing Quality of Herbal Medicines with Reference to Contaminants and Residues, World Health Organization, Geneva, Switzerland (2007)
  

  •  
• 
  46

  WHO Guidelines on Good Agricultural and Collection Practices (GACP) for Medicinal Plants,World Health Organization, Geneva, Switzerland (2003)
  

  •  
• 
  47

  Bekanntmachung von Empfehlungen für Höchstmengen an Schwermetallen bei Arzneimitteln pflanzlicher und tierischer Herkunft (Arzneimittel-Kontaminanten-Empfehlungen – Schwermetalle), Bundesministerium für Gesundheit, German Ministry of Health Promulgation (1991); BMG 355 – 5135
  

  •  
• 
  48

  WHO Monographs on Selected Medicinal Plants,World Health Organization, Geneva, Switzerland (1999), Vol. 1
  

  •  
• 
  49

  Herbal Drugs, monograph 1433, European Pharmacopeia, Strasbourg (2011), 7th ed., Supplement 7.3
  

  •  
• 
  50

  Heavy Metals in Herbal Drugs and Fatty Oils, General Chapter 2.4.27., European Pharmacopoeia, Strasbourg (2002), 4th edition, Supplement 4.4, pp. 3238 – 3239
  

  •  
• 
  51

  Methods in Pharmacognosy, General Chapter 2.8, European Pharmacopoeia, Strasbourg (1996), 3rd edition, pp. 119 – 125
  

  •  

  Kuz’mina, N.E.; Scientific Center for Expert Assessment of Substances for Medicinal Use, Russian Ministry of Health, Building 8, Petrovskii Boulevard, Russian Federation
© Copyright 2016 Elsevier B.V., All rights reserved.